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Kathy McGinn, R.N., B.S.N., L.N.C.C.

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PPHN Symptoms

Symptoms of Persistent Pulmonary Hypertension of the Newborn (PPHN)

The symptoms of PPHN are acute, severe, and often life-threatening, and usually appear within 12 hours after birth.

Visible Symptoms 

The first sign that an infant has PPHN may come in the form of visible symptoms, including:

  • Rapid breathing (tachypnea)
  • Rapid heart rate (tachycardia)
  • Irregular heartbeat
  • Respiratory distress, which may be indicated by flaring nostrils and grunting
  • Bluish tint to the skin (cyanosis), which may be present even if the baby is receiving extra oxygen to assist breathing
  • Lethargy
  • Sweating

Physical Examination 

Upon physical examination, the doctor may note additional symptoms, such as:

  • Heart murmur-an extra or unusual sound heard when listening to the heartbeat
  • Low oxygen levels in the blood, even though the baby is receiving extra oxygen
  • Low blood pressure (hypotension)
  • Weak pulse
  • Swelling in the hands or feet
  • An enlarged liver

In order to diagnose PPHN with certainty, however, the doctor must conduct a more in-depth examination to rule out other possible reasons for the symptoms.

Learn about how PPHN occurs.

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